Influence of age on the association of vascular risk factors with acute stroke (INTERSTROKE): a case–control study

Authors : Catriona Reddin, Graeme J Hankey, John Ferguson, Peter Langhorne, Shahram Oveisgharan, Michelle Canavan, Helle K Iversen, Annika Rosengren, Danuta Ryglewicz, Anna Czlonkowska, Xingyu Wang, Fernando Lanas, Albertino Damasceno, *Denis Xavier*, Patricio Lopez-Jaramillo, Andrew Smyth, Salim Yusuf, Martin O’Donnell

Publication Year : 2025

Abstract :

Background: 

The absolute burden of stroke is increasing due to an ageing population, as well as an increased incidence of stroke in young adults. We aimed to determine whether age modifies the magnitude of association between vascular risk factors and stroke in the INTERSTROKE study.